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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BUB1 All Species: 4.55
Human Site: S436 Identified Species: 25
UniProt: O43683 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43683 NP_004327.1 1085 122375 S436 T H K V A N T S S F H T T P N
Chimpanzee Pan troglodytes XP_001142040 1085 122293 S436 T H K V A N T S S F H T T P N
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O08901 1058 119544 N424 T N K V A S I N D F H T T P N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782910 1533 171372 A700 T P S S A S F A S L S R S R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P41695 1021 117850 H410 N P S Q S T H H K N T Q V Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 N.A. N.A. N.A. 72 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.4
Protein Similarity: 100 99.3 N.A. N.A. N.A. 82.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 42.3
P-Site Identity: 100 100 N.A. N.A. N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 80 0 0 20 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 20 0 0 60 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 40 0 0 0 0 20 20 0 0 60 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 60 0 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 20 0 0 0 40 0 20 0 20 0 0 0 0 80 % N
% Pro: 0 40 0 0 0 0 0 0 0 0 0 0 0 60 0 % P
% Gln: 0 0 0 20 0 0 0 0 0 0 0 20 0 20 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 20 0 20 0 % R
% Ser: 0 0 40 20 20 40 0 40 60 0 20 0 20 0 0 % S
% Thr: 80 0 0 0 0 20 40 0 0 0 20 60 60 0 0 % T
% Val: 0 0 0 60 0 0 0 0 0 0 0 0 20 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _